Subclinical myocardial dysfunction in Rett syndrome
نویسندگان
چکیده
منابع مشابه
Subclinical myocardial dysfunction in Rett syndrome.
AIMS Rett syndrome (RTT) is a rare neurodevelopmental disorder frequently linked to methyl-CpG-binding protein 2 (MeCP2) gene mutations. RTT is associated with a 300-fold increased risk of sudden cardiac death. Rhythm abnormalities and cardiac dysautonomia do not to fully account for cardiac mortality. Conversely, heart function in RTT has not been explored to date. Recent data indicate a previ...
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Rett syndrome, a neurodevelopmental disorder caused by mutations in the X-linked gene encoding methyl-CpG-binding protein 2 (MeCP2), is a leading cause of mental retardation with autistic features in females. MECP2 mutations have also been identified in individuals with a variety of clinical syndromes, including mild learning-disability in females, neonatal encephalopathy in males, and psychiat...
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ژورنال
عنوان ژورنال: European Heart Journal - Cardiovascular Imaging
سال: 2011
ISSN: 2047-2404,2047-2412
DOI: 10.1093/ejechocard/jer256